Tuesday, June 15, 2010

CLINICAL APPLICATION OF
PROTEIN GROWTH FACTORS
IN DAILY OFFICE PROCEDURE

Maya Surjadjaja
Subdepartment of Clinical Nutrition, Dr Mintoharjo Naval Hospital; Gracia Patricia Clinic

Abstract

    Many anti aging facilities offer difference methods and utilized a variety of stem cells as tissue repairmen (mesenchymal bone marrow/fat, haematopoetic), platelet rich plasma, growth factors, growth hormone injection, supplements .Many life cell products  in the today market claimed that their products contain xeno “living” stem cells. Several of the manufacturers on the other hand mentioned that their products are non water soluble peptides (growth factors) with very low molecular weight. It is derived from certain plants or certain young / fetal animal’s extracts (thymus, spleen, placenta, mesenchyme, umbilical etc) cultured with special care from generations. These growth factors are available in many application’s forms, such as injections (iv, im, sc), serums used with micro needle, capsules and creams.
    Everybody is affected by the decrease of the body defense capacity when they are aging. Stress, poor diet, high consume of alcohol and tobaccos also  infection weaken the body resistance significantly. The immunological system is no longer capable to defense the body against some chronic inflammations or metabolic diseases. For rejuvenations purposes, the products could be used to enhance the wound healing; stimulate the growth of collagen, restore acne scars, tightening pores, lighten pigmentation, minimizing fine lines and rehydrate the dry mature skin. Besides these more esthetic indications, in the daily practice those products are used for skin repair in severe burn, hair regrowth in alopecia androgenetica and as an adjuvant therapy for certain degenerative diseases such as diabetes mellitus, cerebro vascular diseases, arthritis and hormonal disturbances especially in andro- and menopausal syndroms as well.
    Some side effects like increased body temperature, swelling and flare reactions at the puncture’s area should be mild and tolerable. Increase in appetite especially in overweight/obese patients should be taken into consideration. In practice, intra venous cortisone, norepinephrine and anti allergic preparations must be reachable in case of a rarely unexpected anaphylactic reaction.

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